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polymethylated quercetin biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
S-adenosyl-L-methionine + Rhamnetin <=> 3,7-O-dimethylquercetin + S-adenosyl-L-homocysteine + H+ 2.1.1

S-adenosyl-L-methionine + quercetin <=> H+ + S-adenosyl-L-homocysteine + quercetin-3-O-methylether 2.1.1.104 caffeoyl-CoA O-methyltransferase
2.1.1.267 flavonoid 3',5'-methyltransferase
2.1.1.42 flavone 3'-O-methyltransferase
2.1.1.68 caffeate O-methyltransferase
2.1.1.76 quercetin 3-O-methyltransferase
2.1.1.B121






S-adenosyl-L-methionine + quercetin-3-O-methylether <=> 3,3''-dimethylquercetin + S-adenosyl-L-homocysteine 2.1.1

S-adenosyl-L-methionine + quercetin <=> H+ + S-adenosyl-L-homocysteine + quercetin-3-O-methylether 2.1.1.104 caffeoyl-CoA O-methyltransferase
2.1.1.267 flavonoid 3',5'-methyltransferase
2.1.1.42 flavone 3'-O-methyltransferase
2.1.1.68 caffeate O-methyltransferase
2.1.1.76 quercetin 3-O-methyltransferase
2.1.1.B121






S-adenosyl-L-methionine + Rhamnetin <=> 7,4''-dimethylquercetin + S-adenosyl-L-homocysteine + H+ 2.1.1

S-adenosyl-L-methionine + quercetin-3-O-methylether <=> S-adenosyl-L-homocysteine + 3,7-O-dimethylquercetin 2.1.1.82 3-methylquercetin 7-O-methyltransferase

S-adenosyl-L-methionine + quercetin <=> Rhamnetin + S-adenosyl-L-homocysteine 2.1.1
2.1.1.267 flavonoid 3',5'-methyltransferase
2.1.1.76 quercetin 3-O-methyltransferase
2.1.1.B75
2.1.1.B76





S-adenosyl-L-methionine + isorhamnetin <=> 3,3''-dimethylquercetin + S-adenosyl-L-homocysteine 2.1.1

S-adenosyl-L-methionine + Rhamnetin <=> 7,3''-dimethylquercetin + S-adenosyl-L-homocysteine + H+ 2.1.1

Visualization of the pathway